Overview
Red rice yeast (red yeast rice) has been used in
Chinese traditional medicine for centuries to
help blood circulation and ease stomach
problems. It is made by growing red yeast on
white rice, and then powdering it.
In the 1970s it was discovered that red rice
yeast lowers high levels of LDL (bad
cholesterol) and triglycerides in the blood. In
1998, the FDA banned the sale of a commercial
dietary supplement called Cholestin which
contained red rice yeast, claiming that the
chemical composition of red rice yeast is nearly
identical to that of the prescription drug
Lovastatin, a statin which is often prescribed
to help lower cholesterol levels. Products
containing red rice yeast may not be sold in the
United States, but are still widely available
throughout the world, and can often be purchased
on the internet.
What Red Rice Yeast Does:
Red rice yeast has been proven to lower levels
of bad cholesterol in the blood as effectively
as most pharmaceutical drugs that are prescribed
to help lower cholesterol levels. In addition,
red rice yeast has been proven in a number of
research studies to help lower high levels of
triglycerides in the blood. Like cholesterol,
trigycerides can affect blood circulation by
clogging blood vessels in the body. Red rice
yeast (or, as it’s more often called – red yeast
rice) contains a substance called monacolin K
which inhibits the production of cholesterol in
the liver. This is exactly the same action that
prescription drugs like lovastatin (Mexacor) and
Lipitor have on the production of cholesterol.
Interestingly, the concentration of monacolin K
in red rice yeast is considerably lower than the
amount of lovastatin usually prescribed as a
daily dose to lower cholesterol – but it still
reduced LDL cholesterol levels by as much as 17%
in just 8 weeks in a study at UCLA. This has led
some doctors and researchers to speculate that
other chemicals in red rice yeast (specifically
sterols) may boost the effect of monacolin K or
actively reduce cholesterol themselves.
Health Benefits of Red Rice Yeast:
A
number of well-constructed and well-documented
studies confirm that red rice yeast
substantially lowers the amount of total
cholesterol and ‘bad’ cholesterol in the blood
without affecting the HDL, ‘good’ cholesterol.
At UCLA, researchers tested the effects of
Cholestin, a red rice yeast product that
contained red rice yeast produced by a
proprietary method that increased the amount of
monacolin K to near pharmaceutical levels. The
results were unmistakable. Those in the study
that took Cholestin reduced LDL cholesterol
levels by as much as 21% over the 12 weeks of
the study, and reduced triglycerides by . In
contrast, those who took a placebo averaged a
reduction of 1%. This is the most
well-documented study and the one most often
cited when referring to red rice yeast, but it’s
important to note that the product used in this
study contains higher levels of monacolin K than
most preparations of red yeast rice though
considerably less than the amount of active
ingredients in most prescription statin drugs.
Possible Side Effects of Red Rice Yeast
Because the active components in red rice yeast
affect the body in ways that are identical to
those of some statin drugs, most doctors advise
patients to treat red rice yeast with the same
caution. The side effects of red rice yeast are
rare and generally mild, but lovastatin has
raised some concerns about compromised liver
function. In addition, doctors and nutritionists
advise that those who are taking statin drugs or
other drugs to lower cholesterol levels should
discuss the possibility of using red rice yeast
as an alternative to conventional drug therapy
rather than in addition to it.
Summary and Conclusion
In 2001, the FDA decided that Cholestin, with
its proprietary formula of red rice yeast,
contained a substance identical to lovastatin, a
drug that is regulated by the FDA. A court
upheld the FDA ruling, and Cholestin was removed
from open store shelves. The manufacturer has
introduced a reformulated Cholestin without red
rice yeast. Following in the steps of NuSkin,
the manufacturers of Cholestin, other
nutraceutical companies also pulled products
containing red rice yeast from the U.S. market.
It is still, however, possible to find red yeast
rice on the Internet.